Vitamin 6 For Your Health

Vitamin B6 manufactured in EU is a water soluble vitamin and a part of Vitamin B group. Pyridoxal phosphate (PLP) is the active form and is involve in many reactions of amino acids metabolism which includes deamination, decarboxylation and transamination. It is also responsible for enzymatic reaction which takes care of glucose from glycogen.

Vitamin B6 manufactured in EU is a water soluble vitamin and a part of Vitamin B group. Pyridoxal phosphate (PLP) is the active form and is involve in many reactions of amino acids metabolism which includes deamination, decarboxylation and transamination. It is also responsible for enzymatic reaction which takes care of glucose from glycogen.

It is essentially to note down that the active form of Vitamin B6 is involve in many aspects of histamine synthesis, haemoglobin synthesis, and neurotransmitter synthesis and macronutrient metabolism. The metabolism of Vitamin B6 takes place at liver. PLP catalyzes transamination reactions that are essential for providing amino acids as a substrate for gluconeogenesis. PLP is also an essential component of two enzymes that converts methionine to Cysteine via two reactions. It is also required for the conversion of tryptophan to niacin and low vitamin B6 status impairs this conversion. PLP plays an important role in the metabolism of selenomethionine to selenohomocysteine and further selenohomocysteine to hydrogen selenide.

Vitamin B6 is also a very important component of enzymes that facilitate the biosynthesis of sphingolipids. Ceramide in particular requires PLP. During this reaction serine is decarboxylated and combined with palmitoyl-CoA to form sphinganine which is combined with a fatty acyl CoA to form dihydroceramide and dihydroceramide is further de saturated to form ceramide. The primary role of vitamin B6 is to act as a coenzyme to many other enzymes in the body that are actively involved in metabolism which is performed primarily by pyridoxal phosphate. The active form is converted into pyridoxal, pyridoxine and pyridoxamine.

The following metabolic processes involves Vitamin B6:: amino acid, glucose, lipid metabolism, neurotransmitter synthesis, haemoglobin synthesis, histamine synthesis and gene expression. Pyridoxal phosphate is a coenzyme needed for the proper function of the enzymes cystathionine synthase and cystathionase. These enzymes work to transform methionine into cysteine. PLP is also needed as a co factor for the enzymes that allow selenium to be used from the dietary form. This hydrogen selenide can then be used to incorporate selenium into selenoproteins. Vitamin B6 is reportedly used to treat nausea and vomiting in early pregnancy along with medicines such as metoclopramide or doxylamine. It is also pro founded from the study that this vitamin can increase dream vividness as it is deeply involved in the conversion of tryptophan to serotonin.

Pyridoxine has a role in avoiding heart disease. It works by preventing the building of homocysteine which damages blood vessel linings, setting the stage for plaque build up when the body tries to heal the damage. A lack of the vitamin may play a role in sensitivity to monosodium glutamate (MSG), a flavour enhancer. This sensitivity can cause headaches, pain and tingling of the upper extremities, nausea, and vomiting. Vitamin B6 is better known for the treatment of premenstrual syndrome. Low vitamin B6 in take can lead to mental depression. It is also suggested that ingestion of vitamin B6 can alleviate some of the many symptoms of an alcoholic hangover and morning sickness from pregnancy.

Visit http://www.lifespanmeds.com/b6vitamin.html for more information on Vitamin B6!

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